# HISTORY 26 May 2016: Saved by mfeuerma using Paint 2.0-beta19 # molecular_function 20160526: root_PTN001519445 has function transmembrane transporter activity (GO:0022857) 20160526: node_PTN000607051 has function monoamine transmembrane transporter activity (GO:0008504) 20160526: Bilateria_PTN000607168 has function acetylcholine transmembrane transporter activity (GO:0005277) 20160526: Bilateria_PTN000607168 has function acetylcholine binding (GO:0042166) 20160526: node_PTN000607051 has function monoamine transmembrane transporter activity (GO:0008504) 20160526: Bilateria_PTN000607052 has function serotonin transmembrane transporter activity (GO:0015222) # cellular_component 20160526: node_PTN000607051 is found in synaptic vesicle (GO:0008021) 20160526: Bilateria_PTN000607168 is found in AP-1 adaptor complex (GO:0030121) 20160526: node_PTN000607051 is found in cell projection (GO:0042995) 20160526: node_PTN000607051 is found in axon terminus (GO:0043679) 20160526: root_PTN001519445 is found in membrane (GO:0016020) 20160526: Bilateria_PTN000607168 is found in AP-2 adaptor complex (GO:0030122) 20160526: node_PTN000607051 is found in terminal bouton (GO:0043195) 20160526: node_PTN000607051 is found in synaptic vesicle membrane (GO:0030672) 20160526: root_PTN001519445 is found in integral component of plasma membrane (GO:0005887) # biological_process 20160526: node_PTN000607051 participates in synaptic transmission (GO:0007268) 20160526: node_PTN000607051 participates in neurotransmitter transport (GO:0006836) 20160526: Bilateria_PTN000607052 participates in aminergic neurotransmitter loading into synaptic vesicle (GO:0015842) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).