# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 18 Nov 2015: redistribution of PTN001160475 from PTHR24003 to PTHR23502 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150409: node_PTN001160475 has function drug transmembrane transporter activity (GO:0015238) # cellular_component 20150409: node_PTN001160475 is found in plasma membrane (GO:0005886) # biological_process 20150409: node_PTN001160475 participates in drug transmembrane transport (GO:0006855) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: Many duplications, very specific substrates and very few experimental annotations lead to very few propagations. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).