# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 17 Mar 2016: Updated by: TOUCHUP-v1.14 18 Nov 2015: redistribution of PTN000627327 from PTHR24063 to PTHR23500 27 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150313: node_PTN000627328 has function sugar:proton symporter activity (GO:0005351) 20150313: node_PTN000756124 has function glucose transmembrane transporter activity (GO:0005355) # cellular_component 20150313: root_PTN000627327 is found in integral component of plasma membrane (GO:0005887) # biological_process 20150313: node_PTN000756124 participates in glucose import (GO:0046323) 20150313: node_PTN000756124 participates in hexose transmembrane transport (GO:0035428) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES 13-March-2015, HM # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).