# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150911: root_PTN000603211 has function transporter activity (GO:0005215) # cellular_component 20150911: root_PTN000603211 is found in integral component of membrane (GO:0016021) 20150911: Euteleostomi_PTN000603311 is found in plasma membrane (GO:0005886) 20150911: Euteleostomi_PTN000603311 is found in endoplasmic reticulum membrane (GO:0005789) 20150911: Euteleostomi_PTN000603216 is found in early endosome membrane (GO:0031901) # biological_process 20150911: root_PTN000603211 participates in transport (GO:0006810) 20150911: Euteleostomi_PTN000603311 participates in bile acid and bile salt transport (GO:0015721) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).