# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140919: root_PTN000602514 has function transferase activity (GO:0016740) 20140919: node_PTN000602515 has function tRNA (guanine-N7-)-methyltransferase activity (GO:0008176) # cellular_component 20140919: node_PTN000602593 is found in plasma membrane (GO:0005886) 20140919: node_PTN000602515 is found in tRNA methyltransferase complex (GO:0043527) # biological_process 20140919: node_PTN000602593 participates in lipid A biosynthetic process (GO:0009245) 20140919: node_PTN000602515 participates in RNA (guanine-N7)-methylation (GO:0036265) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).