# HISTORY 11 Aug 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160811: root_PTN000600336 has function L-malate dehydrogenase activity (GO:0030060) # cellular_component 20160811: root_PTN000600336 is found in cytoplasm (GO:0005737) 20160811: Eumetazoa_PTN001157397 is found in mitochondrion (GO:0005739) 20160811: Eumetazoa_PTN001157397 is found in cytosol (GO:0005829) 20160811: Viridiplantae_PTN000600431 is found in mitochondrion (GO:0005739) 20160811: Viridiplantae_PTN000600431 is found in chloroplast (GO:0009507) # biological_process 20160811: root_PTN000600336 participates in tricarboxylic acid cycle (GO:0006099) 20160811: root_PTN000600336 participates in malate metabolic process (GO:0006108) 20160811: root_PTN000600336 participates in NAD metabolic process (GO:0019674) 20160811: root_PTN000600336 participates in NADH metabolic process (GO:0006734) 20160811: root_PTN000600336 participates in oxaloacetate metabolic process (GO:0006107) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).