# HISTORY 08 May 2016: Saved by suzi using Paint 2.0-beta19 17 Mar 2016: Updated by: TOUCHUP-v1.14 27 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150818: root_PTN000596945 has function protein tyrosine phosphatase activity (GO:0004725) 20150818: Opisthokonta_PTN000596949 has function protein serine/threonine phosphatase activity (GO:0004722) 20150818: Eukaryota_PTN001915120 has function protein serine/threonine phosphatase activity (GO:0004722) 20150818: Opisthokonta_PTN001515873 has function protein serine/threonine phosphatase activity (GO:0004722) 20150818: Opisthokonta_PTN001515873 has function protein tyrosine/serine/threonine phosphatase activity (GO:0008138) # cellular_component 20150818: root_PTN000596945 is found in cytoplasm (GO:0005737) 20150818: node_PTN000596947 is found in nucleus (GO:0005634) 20150818: Opisthokonta_PTN000596949 is found in spindle pole (GO:0000922) 20150818: Opisthokonta_PTN000596949 is found in mitotic spindle (GO:0072686) 20150818: Opisthokonta_PTN000596949 is found in centrosome (GO:0005813) 20150818: Fungi_PTN001155263 is NOT found in centrosome (GO:0005813) # biological_process 20150818: Eukaryota_PTN000597060 participates in cilium morphogenesis (GO:0060271) 20150818: Opisthokonta_PTN000596949 participates in regulation of exit from mitosis (GO:0007096) 20150818: Opisthokonta_PTN000596949 participates in mitotic cell cycle arrest (GO:0071850) 20150818: Opisthokonta_PTN000596949 participates in mitotic spindle midzone assembly (GO:0051256) 20150818: Opisthokonta_PTN000596949 participates in cilium assembly (GO:0042384) 20150818: Euteleostomi_PTN000597166 participates in endothelial cell migration (GO:0043542) 20150818: Euteleostomi_PTN000597187 participates in positive regulation of cell migration (GO:0030335) 20150818: Eukaryota_PTN001915120 participates in positive regulation of ubiquitin protein ligase activity (GO:1904668) 20150818: Bilateria_PTN001155430 participates in G1/S transition of mitotic cell cycle (GO:0000082) 20150818: Bilateria_PTN001155430 participates in cell cycle arrest (GO:0007050) 20150818: Ascomycota_PTN000597039 does NOT participate in cilium assembly (GO:0042384) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).