# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140729: root_PTN000595174 has function protein binding, bridging (GO:0030674) # cellular_component 20140729: root_PTN000595174 is found in HOPS complex (GO:0030897) 20140729: root_PTN000595174 is found in endosome (GO:0005768) # biological_process 20140729: root_PTN000595174 participates in lysosome organization (GO:0007040) 20140729: root_PTN000595174 participates in endosome organization (GO:0007032) 20140729: root_PTN000595174 participates in regulation of SNARE complex assembly (GO:0035542) 20140729: root_PTN000595174 participates in vesicle docking involved in exocytosis (GO:0006904) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: None of the molecular functions (except protein-binding) seems relevant. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).