# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140725: Dikarya_PTN001152985 has function protein anchor (GO:0043495) 20140722: Eumetazoa_PTN001153077 has function protein phosphatase binding (GO:0019903) 20140722: Eumetazoa_PTN001153077 has function alpha-catenin binding (GO:0045294) 20140722: Eumetazoa_PTN001153077 has function cadherin binding (GO:0045296) # cellular_component 20140722: root_PTN000593603 is found in cytoplasm (GO:0005737) 20140722: root_PTN000593603 is found in nucleus (GO:0005634) 20140725: Dikarya_PTN001152985 is found in nucleus-vacuole junction (GO:0071561) 20140722: Eumetazoa_PTN001153077 is found in catenin complex (GO:0016342) # biological_process 20140722: Dikarya_PTN001152985 participates in macroautophagy (GO:0016236) 20140722: Dikarya_PTN001152985 participates in CVT vesicle assembly (GO:0071255) 20140722: Dikarya_PTN001152985 participates in vacuole inheritance (GO:0000011) 20140722: Dikarya_PTN001152985 participates in nucleus-vacuole junction assembly (GO:0071562) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).