# HISTORY 13 Oct 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161013: root_PTN002359305 has function RNA binding (GO:0003723) 20161013: Eukaryota_PTN000592629 has function protein serine/threonine phosphatase inhibitor activity (GO:0004865) 20161013: root_PTN002359305 has function mRNA binding (GO:0003729) 20161013: Eukaryota_PTN000592629 has function protein phosphatase type 1 regulator activity (GO:0008599) # cellular_component 20161013: Bacteria _PTN001152505 is found in cytosol (GO:0005829) 20161013: Eukaryota_PTN000592629 is found in nuclear speck (GO:0016607) 20161013: Streptomyces coelicolor_Q9L252 is NOT found in nucleus (GO:0005634) 20161013: Eukaryota_PTN000592573 is found in nucleus (GO:0005634) # biological_process 20161013: Eukaryota_PTN000592629 participates in negative regulation of protein dephosphorylation (GO:0035308) 20161013: Embryophyta_PTN001152437 participates in production of miRNAs involved in gene silencing by miRNA (GO:0035196) 20161013: Opisthokonta_PTN001152383 participates in production of miRNAs involved in gene silencing by miRNA (GO:0035196) 20161013: Fungi_PTN001152404 participates in mRNA splicing, via spliceosome (GO:0000398) 20161013: Fungi_PTN001152404 participates in maintenance of RNA location (GO:0051237) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).