# HISTORY 26 Aug 2016: Saved by pascalegaudet using Paint 2.22 # molecular_function 20160826: Opisthokonta_PTN001150527 has function structural constituent of cytoskeleton (GO:0005200) 20160826: Eumetazoa_PTN001150528 has function ubiquitin-protein transferase activity (GO:0004842) 20160826: Eumetazoa_PTN001150528 has LOST/MODIFIED function structural constituent of cytoskeleton (GO:0005200) # cellular_component 20160826: Opisthokonta_PTN001150527 is found in cytoskeleton (GO:0005856) 20160826: Eumetazoa_PTN001150528 is NOT found in cytoskeleton (GO:0005856) 20160826: Bilateria_PTN000589691 is found in plasma membrane (GO:0005886) # biological_process 20160826: Opisthokonta_PTN001150527 participates in actomyosin structure organization (GO:0031032) 20160826: Eumetazoa_PTN001150528 participates in protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787) 20160826: Eumetazoa_PTN001150528 does NOT participate in actomyosin structure organization (GO:0031032) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).