# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150819: root_PTN000581728 has function damaged DNA binding (GO:0003684) 20150819: root_PTN000581728 has function 5'-3' exodeoxyribonuclease activity (GO:0035312) # cellular_component 20150819: root_PTN000581728 is found in nuclear chromosome, telomeric region (GO:0000784) # biological_process 20150819: root_PTN000581728 participates in protection from non-homologous end joining at telomere (GO:0031848) 20150819: root_PTN000581728 participates in interstrand cross-link repair (GO:0036297) 20150819: root_PTN000581728 participates in double-strand break repair via nonhomologous end joining (GO:0006303) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).