# HISTORY 16 Aug 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160816: Eukaryota_PTN000575874 has function microtubule binding (GO:0008017) 20160816: Viridiplantae_PTN000575922 has function DNA binding (GO:0003677) # cellular_component 20160816: Eukaryota_PTN000575873 is found in nucleus (GO:0005634) 20160816: Opisthokonta_PTN000575875 is found in kinetochore (GO:0000776) 20160816: Opisthokonta_PTN000575875 is found in spindle matrix (GO:1990047) # biological_process 20160816: Viridiplantae_PTN000575922 participates in regulation of transcription, DNA-templated (GO:0006355) 20160816: Opisthokonta_PTN000575875 participates in mitotic spindle assembly (GO:0090307) 20160816: Opisthokonta_PTN000575875 participates in attachment of spindle microtubules to kinetochore (GO:0008608) 20160816: Opisthokonta_PTN000575875 participates in mitotic spindle assembly checkpoint (GO:0007094) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: In plants the function seems to be totally different ! # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).