# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 17 Mar 2016: Updated by: TOUCHUP-v1.14 27 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150506: Eukaryota_PTN001506181 has function actin filament binding (GO:0051015) # cellular_component 20150506: Eukaryota_PTN001506181 is found in actin cortical patch (GO:0030479) 20150506: Eukaryota_PTN001506181 is found in actin filament (GO:0005884) 20150506: Eumetazoa_PTN001904463 is NOT found in actin cortical patch (GO:0030479) 20150506: Viridiplantae_PTN001143780 is NOT found in actin cortical patch (GO:0030479) 20150506: Dictyostelium_PTN001143425 is NOT found in actin cortical patch (GO:0030479) # biological_process 20150506: Eukaryota_PTN001506181 participates in endocytosis (GO:0006897) 20150506: Eukaryota_PTN001506181 participates in positive regulation of actin nucleation (GO:0051127) 20150506: Eukaryota_PTN001506181 participates in regulation of cell shape (GO:0008360) 20150506: Eukaryota_PTN001506181 participates in actin filament-based movement (GO:0030048) 20150506: Eukaryota_PTN001506181 participates in actin cortical patch assembly (GO:0000147) 20150506: Eukaryota_PTN001506181 participates in actin cortical patch localization (GO:0051666) 20150506: Eumetazoa_PTN001904463 does NOT participate in actin cortical patch assembly (GO:0000147) 20150506: Eumetazoa_PTN001904463 does NOT participate in actin cortical patch localization (GO:0051666) 20150506: Viridiplantae_PTN001143780 does NOT participate in actin cortical patch assembly (GO:0000147) 20150506: Viridiplantae_PTN001143780 does NOT participate in actin cortical patch localization (GO:0051666) 20150506: Dictyostelium_PTN001143425 does NOT participate in actin cortical patch assembly (GO:0000147) 20150506: Dictyostelium_PTN001143425 does NOT participate in actin cortical patch localization (GO:0051666) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).