# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 17 Mar 2016: Updated by: TOUCHUP-v1.14 17 Mar 2016: Updated by: TOUCHUP-v1.14 26 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20151009: root_PTN000554253 has function metallopeptidase activity (GO:0008237) 20151009: root_PTN000554253 has function ATP-dependent peptidase activity (GO:0004176) # cellular_component 20151009: node_PTN000554083 is found in mitochondrion (GO:0005739) 20151009: Eukaryota_PTN000554085 is found in mitochondrial inner membrane (GO:0005743) 20151009: Fungi_PTN001130001 is found in m-AAA complex (GO:0005745) 20151009: Viridiplantae_PTN000554233 is found in chloroplast thylakoid membrane (GO:0009535) 20151009: node_PTN001892202 is found in chloroplast envelope (GO:0009941) 20151009: Eukaryota_PTN001130167 is found in chloroplast thylakoid membrane (GO:0009535) 20151009: Eukaryota_PTN001130167 is found in chloroplast envelope (GO:0009941) 20151009: Eukaryota_PTN001130077 is found in mitochondrial inner membrane (GO:0005743) 20151009: Magnoliophyta_PTN000554318 is found in chloroplast envelope (GO:0009941) 20151009: Bacteria _PTN000554354 is found in plasma membrane (GO:0005886) 20151009: Cyanobacteria_PTN001130180 is NOT found in chloroplast thylakoid membrane (GO:0009535) 20151009: Cyanobacteria_PTN001130180 is NOT found in chloroplast envelope (GO:0009941) 20151009: Eukaryota_PTN001130167 is NOT found in mitochondrion (GO:0005739) # biological_process 20151009: root_PTN000554253 participates in proteolysis (GO:0006508) 20151009: Eukaryota_PTN000554085 participates in protein import into mitochondrial intermembrane space (GO:0045041) 20151009: Eukaryota_PTN000554085 participates in mitochondrial protein processing (GO:0034982) 20151009: Eukaryota_PTN000554085 participates in mitochondrial fusion (GO:0008053) 20151009: Eukaryota_PTN000554085 participates in protein complex assembly (GO:0006461) 20151009: Eukaryota_PTN000554085 participates in cristae formation (GO:0042407) 20151009: Euteleostomi_PTN000554136 participates in nerve development (GO:0021675) 20151009: Opisthokonta_PTN001130045 participates in nervous system development (GO:0007399) 20151009: Opisthokonta_PTN001130045 participates in mitochondrion organization (GO:0007005) 20151009: Opisthokonta_PTN001130045 participates in cell adhesion (GO:0007155) 20151009: Embryophyta_PTN001130034 participates in embryo development ending in seed dormancy (GO:0009793) 20151009: Embryophyta_PTN001130073 participates in chloroplast fission (GO:0010020) 20151009: Embryophyta_PTN001130036 participates in embryo development ending in seed dormancy (GO:0009793) 20151009: Eukaryota_PTN001130167 participates in photosystem II repair (GO:0010206) 20151009: Eukaryota_PTN001130167 participates in thylakoid membrane organization (GO:0010027) 20151009: Eukaryota_PTN001130167 participates in photoinhibition (GO:0010205) 20151009: Eukaryota_PTN001130167 participates in PSII associated light-harvesting complex II catabolic process (GO:0010304) 20151009: Eukaryota_PTN001130077 participates in misfolded or incompletely synthesized protein catabolic process (GO:0006515) 20151009: Eukaryota_PTN001130077 participates in mitochondrion organization (GO:0007005) 20151009: Magnoliophyta_PTN000554318 participates in PSII associated light-harvesting complex II catabolic process (GO:0010304) 20151009: Bacteria _PTN000554354 participates in protein catabolic process (GO:0030163) 20151009: Cyanobacteria_PTN001130180 does NOT participate in thylakoid membrane organization (GO:0010027) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).