# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 17 Mar 2016: Updated by: TOUCHUP-v1.14 18 Nov 2015: redistribution of PTN000860688 from PTHR10959 to PTHR23065 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function # cellular_component 20140924: Opisthokonta_PTN000860688 is found in endosome (GO:0005768) # biological_process 20140924: Opisthokonta_PTN000860688 participates in regulation of endocytosis (GO:0030100) 20140924: Euteleostomi_PTN000102991 participates in neuron projection morphogenesis (GO:0048812) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Annotated by VH and reviewed by PG. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).