# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
17 Mar 2016: Updated by: TOUCHUP-v1.14
17 Mar 2016: Updated by: TOUCHUP-v1.14
26 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20140815: root_PTN000540563 has function protein kinase activity (GO:0004672) 
20140815: Eumetazoa_PTN001121970 has function protein serine/threonine kinase activity (GO:0004674) 

# cellular_component
20140815: Eumetazoa_PTN001121970 is found in mitochondrion (GO:0005739) 
20140815: Euteleostomi_PTN000540589 is found in actin cytoskeleton (GO:0015629) 
20140815: Euteleostomi_PTN000540589 is found in focal adhesion (GO:0005925) 

# biological_process
20140815: Eumetazoa_PTN001121970 participates in positive regulation of mitochondrial fission (GO:0090141) 
20140815: Eumetazoa_PTN001121970 participates in regulation of apoptotic process (GO:0042981) 
20140815: Eumetazoa_PTN001121970 participates in mitophagy (GO:0000422) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
MAF: PINK1 is clearly mitochondrial and regulates apoptosis and mitophagy. Would have prefered a regulation term for mitophagy. It is not clear wether apoptotic regulation is positive or negative when lookingprimary annotation.
The upper branch including  PEAK1 has annotation as probable tyrosine kinase (no exp evidence) and is not mitochondrial.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).