# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 17 Mar 2016: Updated by: TOUCHUP-v1.14 17 Mar 2016: Updated by: TOUCHUP-v1.14 26 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20140728: root_PTN000535793 has function amino acid transmembrane transporter activity (GO:0015171) 20140728: Fungi_PTN001119056 has function L-glutamine transmembrane transporter activity (GO:0015186) 20140728: Fungi_PTN001119056 has function L-isoleucine transmembrane transporter activity (GO:0015188) 20140728: Fungi_PTN001119056 has function L-tyrosine transmembrane transporter activity (GO:0005302) 20140728: Euteleostomi_PTN000536612 has function L-alanine transmembrane transporter activity (GO:0015180) 20140728: Euteleostomi_PTN000536612 has function L-asparagine transmembrane transporter activity (GO:0015182) 20140728: Euteleostomi_PTN000536612 has function L-methionine transmembrane transporter activity (GO:0015191) 20140728: Euteleostomi_PTN000536612 has function L-serine transmembrane transporter activity (GO:0015194) 20140728: Euteleostomi_PTN000536612 has function L-aspartate transmembrane transporter activity (GO:0015183) 20140728: Euteleostomi_PTN000536612 has function L-histidine transmembrane transporter activity (GO:0005290) 20140728: Euteleostomi_PTN000536612 has function L-glutamate transmembrane transporter activity (GO:0005313) 20140728: Euteleostomi_PTN000536612 has function L-glutamine transmembrane transporter activity (GO:0015186) 20140728: Euteleostomi_PTN000536612 has function L-leucine transmembrane transporter activity (GO:0015190) 20140728: Euteleostomi_PTN000536127 has function L-proline transmembrane transporter activity (GO:0015193) 20140728: Euteleostomi_PTN000536127 has function L-alanine transmembrane transporter activity (GO:0015180) 20140728: Euteleostomi_PTN000536127 has function hydrogen:amino acid symporter activity (GO:0005280) 20140728: Euteleostomi_PTN000536127 has function glycine transmembrane transporter activity (GO:0015187) 20140728: Euteleostomi_PTN000536127 has function hydrogen ion transmembrane transporter activity (GO:0015078) 20140728: Fungi_PTN001119154 has function L-histidine transmembrane transporter activity (GO:0005290) 20140728: Fungi_PTN001119154 has function L-serine transmembrane transporter activity (GO:0015194) 20140728: Fungi_PTN001119154 has function L-arginine transmembrane transporter activity (GO:0061459) 20140728: Fungi_PTN001119154 has function L-glutamate transmembrane transporter activity (GO:0005313) 20140728: Fungi_PTN001119154 has function L-lysine transmembrane transporter activity (GO:0015189) 20140728: Fungi_PTN001119154 has function L-tyrosine transmembrane transporter activity (GO:0005302) 20140728: Euteleostomi_PTN000536443 has function glycine transmembrane transporter activity (GO:0015187) 20140728: Euteleostomi_PTN000536413 has function L-histidine transmembrane transporter activity (GO:0005290) 20140728: Euteleostomi_PTN000536413 has function L-glutamine transmembrane transporter activity (GO:0015186) 20140728: Euteleostomi_PTN000536413 has function L-asparagine transmembrane transporter activity (GO:0015182) # cellular_component 20140728: Fungi_PTN001119056 is found in vacuolar membrane (GO:0005774) 20140728: Embryophyta_PTN001118962 is found in plasma membrane (GO:0005886) 20140728: Embryophyta_PTN001118971 is found in plasma membrane (GO:0005886) 20140728: Embryophyta_PTN001118966 is found in plasma membrane (GO:0005886) 20140728: Opisthokonta_PTN001118982 is found in endoplasmic reticulum (GO:0005783) 20140728: Fungi_PTN001119154 is found in fungal-type vacuole membrane (GO:0000329) 20140728: node_PTN000536384 is found in integral component of plasma membrane (GO:0005887) 20140728: Eukaryota_PTN001119389 is found in vacuolar membrane (GO:0005774) 20140728: Embryophyta_PTN001119085 is found in plasma membrane (GO:0005886) # biological_process 20140728: root_PTN000535793 participates in amino acid transmembrane transport (GO:0003333) 20140728: Euteleostomi_PTN000536612 participates in L-alanine transport (GO:0015808) 20140728: Euteleostomi_PTN000536612 participates in aspartate transport (GO:0015810) 20140728: Euteleostomi_PTN000536612 participates in asparagine transport (GO:0006867) 20140728: Euteleostomi_PTN000536612 participates in L-serine transport (GO:0015825) 20140728: Euteleostomi_PTN000536127 participates in glycine transport (GO:0015816) 20140728: Euteleostomi_PTN000536413 participates in histidine transport (GO:0015817) 20140728: Euteleostomi_PTN000536413 participates in glutamine transport (GO:0006868) 20140728: Euteleostomi_PTN000536413 participates in asparagine transport (GO:0006867) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).