# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 17 Mar 2016: Updated by: TOUCHUP-v1.14 26 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150911: Metazoa_PTN001861954 has function semaphorin receptor activity (GO:0017154) # cellular_component 20150911: Metazoa_PTN001861954 is found in integral component of plasma membrane (GO:0005887) 20150911: Metazoa_PTN001861954 is found in semaphorin receptor complex (GO:0002116) # biological_process 20150911: Metazoa_PTN001861954 participates in regulation of cell migration (GO:0030334) 20150911: Metazoa_PTN001861954 participates in semaphorin-plexin signaling pathway involved in axon guidance (GO:1902287) 20150911: Bilateria_PTN001861955 participates in negative regulation of cell adhesion (GO:0007162) 20150911: Bilateria_PTN001861955 participates in regulation of GTPase activity (GO:0043087) 20150911: Bilateria_PTN001861955 participates in positive regulation of axonogenesis (GO:0050772) 20150911: Bilateria_PTN001861955 participates in regulation of cell shape (GO:0008360) 20150911: Euteleostomi_PTN000504831 participates in axon extension (GO:0048675) 20150911: Euteleostomi_PTN000504785 participates in negative regulation of cell migration (GO:0030336) 20150911: Bilateria_PTN000504672 participates in motor neuron axon guidance (GO:0008045) 20150911: Bilateria_PTN000504672 participates in regulation of axon extension involved in axon guidance (GO:0048841) 20150911: Chordata_PTN001476654 participates in branchiomotor neuron axon guidance (GO:0021785) 20150911: Euteleostomi_PTN000504676 participates in endothelial cell migration (GO:0043542) 20150911: Ecdysozoa_PTN000504953 participates in sensory neuron axon guidance (GO:0097374) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).