# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140604: Eukaryota_PTN000504505 has function cysteine-type endopeptidase activity (GO:0004197) # cellular_component 20140604: Eukaryota_PTN000504505 is found in cytosol (GO:0005829) # biological_process 20140604: Eukaryota_PTN000504505 participates in protein targeting to membrane (GO:0006612) 20140604: Eukaryota_PTN000504505 participates in mitophagy (GO:0000422) 20140604: Eukaryota_PTN000504505 participates in C-terminal protein lipidation (GO:0006501) 20140604: Eukaryota_PTN000504505 participates in protein processing (GO:0016485) 20140604: Eukaryota_PTN000504505 participates in protein delipidation (GO:0051697) 20140604: Eukaryota_PTN000504505 participates in autophagosome assembly (GO:0000045) 20140611: Eukaryota_PTN000504505 participates in nucleophagy (GO:0044804) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES PG-MAF 2014-06-11 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).