# HISTORY 12 Oct 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161012: Opisthokonta_PTN001476056 contributes to function histone methyltransferase activity (GO:0042054) 20161012: Eukaryota_PTN000502888 has function chromatin DNA binding (GO:0031490) # cellular_component 20161012: Opisthokonta_PTN001476056 is found in ESC/E(Z) complex (GO:0035098) 20161012: Opisthokonta_PTN000502889 is found in RSC complex (GO:0016586) 20161012: Eukaryota_PTN000502888 is found in nucleus (GO:0005634) # biological_process 20161012: Eukaryota_PTN000502888 participates in regulation of transcription, DNA-templated (GO:0006355) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).