# HISTORY 16 Jun 2016: Saved by mfeuerma using Paint 2.0-beta19 # molecular_function 20160616: Bacteria _PTN000496372 has function 2-dehydropantoate 2-reductase activity (GO:0008677) 20160616: Bacteria _PTN000496372 has function NADP binding (GO:0050661) 20160616: Fungi_PTN001093729 has function translation regulator activity (GO:0045182) # cellular_component 20160616: Fungi_PTN001093729 is found in mitochondrion (GO:0005739) 20160616: node_PTN000496361 is found in cytosol (GO:0005829) 20160616: root_PTN000496347 is found in cytoplasm (GO:0005737) # biological_process 20160616: Fungi_PTN001093729 participates in positive regulation of mitochondrial translation (GO:0070131) 20160616: Fungi_PTN001093729 participates in mitochondrial respiratory chain complex III biogenesis (GO:0097033) 20160616: Bacteria _PTN000496372 participates in pantothenate biosynthetic process from valine (GO:0033317) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).