# HISTORY 17 Aug 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160817: Euarchontoglires_PTN000493179 has function calmodulin binding (GO:0005516) 20160817: Amniota_PTN001855124 has function calmodulin binding (GO:0005516) # cellular_component 20160817: Euarchontoglires_PTN000493179 is found in acrosomal vesicle (GO:0001669) # biological_process 20160817: Euarchontoglires_PTN000493179 participates in positive regulation of acrosome reaction (GO:2000344) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: Due to the many duplications, it is almost impossible to propagate the annotations for MF and BPs, however they all have the IQ calmodulin-binding motif. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).