# HISTORY 19 May 2016: Saved by mfeuerma using Paint 2.0-beta19 # molecular_function 20160519: Metazoa_PTN001838790 has function transcription factor activity, sequence-specific DNA binding (GO:0003700) 20160519: Metazoa_PTN001838790 has function RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978) 20160519: Metazoa_PTN001838790 has function core promoter sequence-specific DNA binding (GO:0001046) # cellular_component 20160519: Metazoa_PTN001838790 is found in nucleus (GO:0005634) 20160519: Metazoa_PTN001838790 is found in transcription factor complex (GO:0005667) # biological_process 20160519: Metazoa_PTN001838790 participates in regulation of transcription from RNA polymerase II promoter (GO:0006357) 20160519: Metazoa_PTN001838790 participates in multicellular organism development (GO:0007275) 20160519: Metazoa_PTN001838774 participates in Ras protein signal transduction (GO:0007265) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).