# HISTORY 23 May 2016: Saved by krc using Paint 2.0-beta19 # molecular_function 20160523: Eukaryota_PTN000458182 has function unfolded protein binding (GO:0051082) # cellular_component 20160523: Eukaryota_PTN000458182 is found in preribosome, large subunit precursor (GO:0030687) # biological_process 20160523: Eukaryota_PTN000458182 participates in ribosomal large subunit biogenesis (GO:0042273) # PRUNED 23 May 2016: Euteleostomi_PTN001459739 has been pruned from tree # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES - 9EUTE:PTN0001459739 - This set of vertebrate sequences has a long branch length from the duplication node above. These sequences all look good together, but look rather different than all the other sequences in the tree, which look really good against each other.=> PRUNED # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).