# HISTORY 11 Aug 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160811: Euteleostomi_PTN000455582 has function Toll-like receptor binding (GO:0035325) 20160811: node_PTN000790271 has function transcription regulatory region DNA binding (GO:0044212) 20160811: Ecdysozoa_PTN000455664 has function potassium channel regulator activity (GO:0015459) # cellular_component 20160811: Ecdysozoa_PTN000455664 is found in striated muscle dense body (GO:0055120) 20160811: Ecdysozoa_PTN000455664 is found in plasma membrane (GO:0005886) # biological_process 20160811: node_PTN000790271 participates in regulation of transcription from RNA polymerase II promoter (GO:0006357) 20160811: node_PTN000790271 participates in fatty acid catabolic process (GO:0009062) 20160811: Euteleostomi_PTN000455582 participates in toll-like receptor 3 signaling pathway (GO:0034138) 20160811: Euteleostomi_PTN000455582 participates in toll-like receptor 9 signaling pathway (GO:0034162) 20160811: Euteleostomi_PTN000455582 participates in toll-like receptor 7 signaling pathway (GO:0034154) 20160811: Ecdysozoa_PTN000455664 participates in regulation of muscle contraction (GO:0006937) 20160811: Ecdysozoa_PTN000455664 participates in regulation of potassium ion transport (GO:0043266) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: promary annotation not coherent throughout the tree ! No common MF or BP identified ! # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).