# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20160205: root_PTN000445775 has function phosphatase activity (GO:0016791) 20160205: Metazoa_PTN001830595 has function inorganic diphosphatase activity (GO:0004427) 20160205: Metazoa_PTN001830595 has function phosphohistidine phosphatase activity (GO:0008969) 20160205: Fungi_PTN001060795 has function alkaline phosphatase activity (GO:0004035) 20160205: Deuterostomia_PTN000445814 has function phosphoprotein phosphatase activity (GO:0004721) 20160205: Tetrapoda_PTN000445841 has function nucleotide phosphatase activity, acting on free nucleotides (GO:0098519) 20160205: Bacteria _PTN001830694 has function 5'-nucleotidase activity (GO:0008253) 20160205: Eukaryota_PTN000751264 has function phosphatidylglycerophosphatase activity (GO:0008962) # cellular_component 20160205: Metazoa_PTN001830595 is found in cytosol (GO:0005829) 20160205: Eukaryota_PTN000445812 is found in cytosol (GO:0005829) 20160205: Bacteria _PTN001830694 is found in cytosol (GO:0005829) # biological_process 20160205: root_PTN000445775 participates in dephosphorylation (GO:0016311) 20160205: Metazoa_PTN001830595 participates in protein dephosphorylation (GO:0006470) 20160205: Fungi_PTN001060795 participates in 4-nitrophenol catabolic process (GO:0046196) 20160205: Bacteria _PTN001830694 participates in UMP catabolic process (GO:0046050) 20160205: Eukaryota_PTN000751264 participates in cardiolipin biosynthetic process (GO:0032049) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).