# HISTORY 21 Oct 2016: Saved by pgaudet using Paint 2.22 # molecular_function 20161021: Opisthokonta_PTN000443979 has function actin binding (GO:0003779) 20161021: Opisthokonta_PTN000443979 has function actin filament binding (GO:0051015) 20161021: Eumetazoa_PTN001059856 has function structural constituent of muscle (GO:0008307) # cellular_component 20161021: Trichoplax adhaerens_B3RL32 is NOT found in muscle thin filament tropomyosin (GO:0005862) 20161021: Trichoplax adhaerens_B3S827 is NOT found in muscle thin filament tropomyosin (GO:0005862) 20161021: Eumetazoa_PTN001059856 is found in muscle thin filament tropomyosin (GO:0005862) 20161021: Fungi_PTN001059921 is found in actomyosin contractile ring (GO:0005826) 20161021: Opisthokonta_PTN000443979 is found in actin filament (GO:0005884) # biological_process 20161021: Fungi_PTN001059921 participates in mitotic cytokinesis (GO:0000281) 20161021: Euteleostomi_PTN000444047 participates in cardiac muscle contraction (GO:0060048) 20161021: Opisthokonta_PTN000443979 participates in actin filament organization (GO:0007015) 20161021: Trichoplax adhaerens_B3RL32 does NOT participate in muscle contraction (GO:0006936) 20161021: Trichoplax adhaerens_B3S827 does NOT participate in muscle contraction (GO:0006936) 20161021: Eumetazoa_PTN001059856 participates in muscle contraction (GO:0006936) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).