# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20141114: root_PTN000440615 has function glycerol channel activity (GO:0015254) 20141114: root_PTN000440615 has function water channel activity (GO:0015250) 20141114: Euteleostomi_PTN000440664 has function ammonium transmembrane transporter activity (GO:0008519) 20141114: Euteleostomi_PTN000440664 has function carbon dioxide transmembrane transporter activity (GO:0035379) 20141114: node_PTN000441001 has function urea transmembrane transporter activity (GO:0015204) # cellular_component 20141114: root_PTN000440615 is found in integral component of plasma membrane (GO:0005887) 20141114: Euteleostomi_PTN000440664 is found in basolateral plasma membrane (GO:0016323) 20141114: Viridiplantae_PTN000440860 is found in vacuole (GO:0005773) 20141114: Viridiplantae_PTN000440860 is found in plasmodesma (GO:0009506) 20141114: Euteleostomi_PTN000440693 is found in apical plasma membrane (GO:0016324) 20141114: Euteleostomi_PTN000440781 is found in basolateral plasma membrane (GO:0016323) 20141114: Embryophyta_PTN001058022 is found in central vacuole (GO:0042807) 20141114: Embryophyta_PTN001058022 is found in plant-type vacuole membrane (GO:0009705) # biological_process 20141114: root_PTN000440615 participates in ion transmembrane transport (GO:0034220) 20141114: root_PTN000440615 participates in cellular water homeostasis (GO:0009992) 20141114: Euteleostomi_PTN000440664 participates in ammonium transmembrane transport (GO:0072488) 20141114: node_PTN000441001 participates in urea transmembrane transport (GO:0071918) 20141114: Deuterostomia_PTN000440999 participates in carbohydrate transmembrane transport (GO:0034219) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED ## Annotations that have been removed. 20141114: root_PTN000440615 to cellular response to stress (GO:0033554) is an excluded term and not to be used for annotation # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).