# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20151113: Eukaryota_PTN000429848 contributes to function ATP-dependent DNA helicase activity (GO:0004003) 20151113: Eukaryota_PTN000429848 has function adenylate kinase activity (GO:0004017) 20151113: Eukaryota_PTN000429848 contributes to function single-stranded DNA endodeoxyribonuclease activity (GO:0000014) 20151113: Eukaryota_PTN000429848 has function double-stranded telomeric DNA binding (GO:0003691) 20151113: Eukaryota_PTN000429848 has function single-stranded telomeric DNA binding (GO:0043047) 20151113: Eukaryota_PTN000429848 contributes to function 3'-5' exonuclease activity (GO:0008408) 20151113: Eukaryota_PTN000429848 has function G-quadruplex DNA binding (GO:0051880) # cellular_component 20151113: Eukaryota_PTN000429848 is found in site of double-strand break (GO:0035861) 20151113: Eukaryota_PTN000429848 is found in Mre11 complex (GO:0030870) 20151113: Eukaryota_PTN000429848 is found in condensed nuclear chromosome (GO:0000794) 20151113: Eukaryota_PTN000429848 is found in nuclear chromatin (GO:0000790) 20151113: Eukaryota_PTN000429848 is found in nuclear chromosome, telomeric region (GO:0000784) # biological_process 20151113: Eukaryota_PTN000429848 participates in reciprocal meiotic recombination (GO:0007131) 20151113: Eukaryota_PTN000429848 participates in telomere maintenance via telomerase (GO:0007004) 20151113: Eukaryota_PTN000429848 participates in telomere capping (GO:0016233) 20151113: Eukaryota_PTN000429848 participates in double-strand break repair via homologous recombination (GO:0000724) 20151113: Eukaryota_PTN000429848 participates in DNA duplex unwinding (GO:0032508) 20151113: Eukaryota_PTN000429848 participates in chromosome organization involved in meiotic cell cycle (GO:0070192) 20151113: Eukaryota_PTN000429848 participates in telomere maintenance via recombination (GO:0000722) 20151113: Eukaryota_PTN000429848 participates in nucleic acid phosphodiester bond hydrolysis (GO:0090305) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).