# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20131125: Eumetazoa_PTN001050482 has function ligand-dependent nuclear receptor transcription coactivator activity (GO:0030374) # cellular_component 20131125: Eumetazoa_PTN001050482 is found in nucleus (GO:0005634) # biological_process 20131125: Eumetazoa_PTN001050482 participates in positive regulation of receptor activity (GO:2000273) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES family picked through paint-apoptosis project. pmid:14517287 show human sra1 overexpression enhanced apoptosis in mammary epithelia, annotation to 'execution phase of apoptosis' go:0097194 need to be re-annotate. ln # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).