# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140619: Eukaryota_PTN000426471 has function protein serine/threonine kinase activity (GO:0004674) # cellular_component 20140619: Eukaryota_PTN000426471 is found in nuclear pore (GO:0005643) 20140619: Eukaryota_PTN000426471 is found in late endosome (GO:0005770) 20140619: Eukaryota_PTN000426471 is found in phosphatidylinositol 3-kinase complex, class III, type II (GO:0034272) 20140619: Eukaryota_PTN000426471 is found in nucleus-vacuole junction (GO:0071561) 20140619: Eukaryota_PTN000426471 is found in phosphatidylinositol 3-kinase complex, class III, type I (GO:0034271) # biological_process 20140619: Eukaryota_PTN000426471 participates in pexophagy (GO:0030242) 20140619: Eukaryota_PTN000426471 participates in protein targeting to vacuole (GO:0006623) 20140619: Eukaryota_PTN000426471 participates in protein phosphorylation (GO:0006468) 20140619: Eukaryota_PTN000426471 participates in macroautophagy (GO:0016236) 20140619: Eukaryota_PTN000426471 participates in late endosome to vacuole transport (GO:0045324) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: misses "Autophagic vacuole assembly" Is component of PIK3 complex I (with PIK3C3/VPS34, BECN1/ATG6, ATG14, AND in yeast ATG38. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).