# HISTORY 01 Jun 2016: Saved by pascalegaudet using Paint 2.0-beta19 # molecular_function 20160601: Bilateria_PTN000415982 has function arginine transmembrane transporter activity (GO:0015181) 20160601: Bilateria_PTN000415982 has function L-lysine transmembrane transporter activity (GO:0015189) 20160601: Eukaryota_PTN000415968 has function basic amino acid transmembrane transporter activity (GO:0015174) 20160601: Tetrapoda_PTN001044819 has LOST/MODIFIED function L-lysine transmembrane transporter activity (GO:0015189) 20160601: Tetrapoda_PTN001044819 has LOST/MODIFIED function arginine transmembrane transporter activity (GO:0015181) 20160601: Tetrapoda_PTN001044819 has LOST/MODIFIED function basic amino acid transmembrane transporter activity (GO:0015174) 20160601: Schizosaccharomyces pombe_SPAC17C9.10 has LOST/MODIFIED function basic amino acid transmembrane transporter activity (GO:0015174) # cellular_component 20160601: root_PTN001044753 is found in integral component of membrane (GO:0016021) 20160601: Fungi_PTN001044850 is found in integral component of fungal-type vacuolar membrane (GO:0071627) 20160601: Bilateria_PTN000415982 is found in lysosomal membrane (GO:0005765) 20160601: Tetrapoda_PTN001044819 is NOT found in integral component of membrane (GO:0016021) 20160601: Tetrapoda_PTN001044819 is NOT found in lysosomal membrane (GO:0005765) 20160601: Schizosaccharomyces pombe_SPAC17C9.10 is NOT found in integral component of fungal-type vacuolar membrane (GO:0071627) # biological_process 20160601: Fungi_PTN001044850 participates in basic amino acid transmembrane export from vacuole (GO:0034488) 20160601: Bilateria_PTN000415982 participates in L-lysine transmembrane transport (GO:1903401) 20160601: Bilateria_PTN000415982 participates in arginine transmembrane transport (GO:1903826) 20160601: Schizosaccharomyces pombe_SPAC17C9.10 does NOT participate in basic amino acid transmembrane export from vacuole (GO:0034488) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).