# HISTORY 17 Aug 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160817: Eukaryota_PTN001815042 has function ubiquitin binding (GO:0043130) # cellular_component 20160817: Eukaryota_PTN001815042 is found in ESCRT I complex (GO:0000813) # biological_process 20160817: Eukaryota_PTN001815042 participates in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).