# HISTORY 25 Aug 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160825: Eumetazoa_PTN001813090 has function GTPase activator activity (GO:0005096) # cellular_component 20160825: Euteleostomi_PTN001813095 is found in cytoplasm (GO:0005737) 20160825: Euteleostomi_PTN001813095 is found in plasma membrane (GO:0005886) 20160825: Euteleostomi_PTN001039337 is found in lamellipodium (GO:0030027) 20160825: Euteleostomi_PTN000404766 is found in cell cortex (GO:0005938) 20160825: Euteleostomi_PTN000404766 is found in actin cytoskeleton (GO:0015629) # biological_process 20160825: Eumetazoa_PTN001813090 participates in small GTPase mediated signal transduction (GO:0007264) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).