# HISTORY 16 Aug 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160816: Eukaryota_PTN001812651 has function sequence-specific DNA binding (GO:0043565) 20160816: Eukaryota_PTN001812651 has function double-stranded DNA binding (GO:0003690) # cellular_component 20160816: Eukaryota_PTN001812651 is found in nucleus (GO:0005634) # biological_process 20160816: Theria _PTN000402950 participates in intracellular estrogen receptor signaling pathway (GO:0030520) 20160816: Eukaryota_PTN001812651 participates in regulation of transcription from RNA polymerase II promoter (GO:0006357) 20160816: Theria _PTN000750570 participates in regulation of androgen receptor signaling pathway (GO:0060765) 20160816: Eukaryota_PTN001812651 participates in regulation of mRNA processing (GO:0050684) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).