# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140731: Eukaryota_PTN000399700 contributes to function RNA polymerase III activity (GO:0001056) # cellular_component 20140731: Eukaryota_PTN000399700 is found in DNA-directed RNA polymerase III complex (GO:0005666) # biological_process 20140731: Eukaryota_PTN000399700 participates in transcription initiation from RNA polymerase III promoter (GO:0006384) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES This family comprises a conserved subunit, referred to as RPC17 or RPC9, of the multisubunit DNA-dependent RNA polymerase III enzyme in eukaryotes. I did not propagate the annotations related to the Calcitonin gene-related peptide-receptor component protein aspect, e.g. terms like "calcitonin gene-related polypeptide receptor activity" as I wasn't really convinced that this represented a real function versus an artifactual experimental situation. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).