# HISTORY 09 Jul 2016: Updated by: TOUCHUP-v1.19 20 Apr 2016: Saved by pascalegaudet using Paint 2.0-beta15 # molecular_function 20160420: Euteleostomi_PTN001033884 has function transcription factor binding (GO:0008134) 20160420: Euteleostomi_PTN000393143 has function transcription factor binding (GO:0008134) # cellular_component 20160420: Amniota_PTN000393119 is found in nucleus (GO:0005634) 20160420: Amniota_PTN000393119 is found in cytoplasm (GO:0005737) 20160420: Euteleostomi_PTN000393143 is found in nucleus (GO:0005634) 20160420: Euteleostomi_PTN000393143 is found in cytoplasm (GO:0005737) # biological_process 20160420: Amniota_PTN000393119 participates in negative regulation of transcription, DNA-templated (GO:0045892) 20160420: Euteleostomi_PTN000393143 participates in negative regulation of transcription, DNA-templated (GO:0045892) 20160420: Tetrapoda_PTN000393144 participates in positive regulation of viral transcription (GO:0050434) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).