# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function # cellular_component 20140729: Euteleostomi_PTN000392047 is found in nucleus (GO:0005634) # biological_process 20140729: Euteleostomi_PTN000392047 participates in negative regulation of toll-like receptor signaling pathway (GO:0034122) 20140729: Euteleostomi_PTN000392047 participates in I-kappaB kinase/NF-kappaB signaling (GO:0007249) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES No MF terms. CC and BP terms are annotated to the verbetrate node. There are 7 genes for the same uniprot id in the tree. 7/29/2014, HM # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).