# HISTORY 16 Jun 2016: Saved by mfeuerma using Paint 2.0-beta19 # molecular_function # cellular_component 20160616: Eukaryota_PTN000372199 is found in mitochondrion (GO:0005739) 20160616: Euteleostomi_PTN001425502 is found in integral component of mitochondrial inner membrane (GO:0031305) # biological_process 20160616: Fungi_PTN001024045 participates in mitochondrial respiratory chain complex IV assembly (GO:0033617) 20160616: Euteleostomi_PTN001425502 participates in mitochondrial calcium ion transport (GO:0006851) 20160616: Euteleostomi_PTN001425502 participates in calcium ion import (GO:0070509) 20160616: Euteleostomi_PTN001425502 participates in positive regulation of mitochondrial calcium ion concentration (GO:0051561) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).