# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
16 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20160202: Amniota_PTN000366716 has function cadherin binding involved in cell-cell adhesion (GO:0098641) 

# cellular_component
20160202: Eukaryota_PTN001799275 is found in integral component of plasma membrane (GO:0005887) 
20160202: Amniota_PTN000750186 is found in nucleus (GO:0005634) 
20160202: Amniota_PTN000750186 is found in extracellular space (GO:0005615) 
20160202: Amniota_PTN000366716 is found in bicellular tight junction (GO:0005923) 

# biological_process
20160202: Eukaryota_PTN001799275 participates in cell-cell adhesion (GO:0098609) 
20160202: Amniota_PTN000750186 participates in positive regulation of stem cell differentiation (GO:2000738) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
TACSTD2 is cleaved into two products: an extracellular domain and an intracellular domain.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).