# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function # cellular_component 20140930: Opisthokonta_PTN001016925 is found in microtubule cytoskeleton (GO:0015630) 20140930: Opisthokonta_PTN001016925 is found in cytoplasm (GO:0005737) # biological_process 20140930: Opisthokonta_PTN001016925 participates in microtubule cytoskeleton organization (GO:0000226) 20140930: Opisthokonta_PTN001016925 participates in cell proliferation (GO:0008283) 20140930: Bilateria_PTN000357964 participates in cerebral cortex development (GO:0021987) 20140930: Fungi_PTN001794664 does NOT participate in cell proliferation (GO:0008283) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).