# HISTORY 11 Jan 2017: Saved by pgaudet using Paint 2.22 # molecular_function 20170111: Gammaproteobacteria_PTN001015057 has function tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity (GO:0004808) 20170111: root_PTN000354057 has function oxidoreductase activity (GO:0016491) 20170111: Eumetazoa_PTN001014783 has function sarcosine dehydrogenase activity (GO:0008480) 20170111: Eumetazoa_PTN002302648 has function dimethylglycine dehydrogenase activity (GO:0047865) 20170111: Proteobacteria_PTN000354644 has function D-amino-acid dehydrogenase activity (GO:0008718) # cellular_component 20170111: root_PTN000354057 is found in cytoplasm (GO:0005737) 20170111: node_PTN001792533 is found in mitochondrion (GO:0005739) 20170111: Eukaryota_PTN001014659 is NOT found in mitochondrion (GO:0005739) 20170111: Eukaryota_PTN000354502 is found in mitochondrial respiratory chain complex I (GO:0005747) 20170111: Opisthokonta_PTN002302636 is found in mitochondrial matrix (GO:0005759) 20170111: Dikarya_PTN001014663 is found in late endosome (GO:0005770) 20170111: Proteobacteria_PTN000354644 is found in plasma membrane (GO:0005886) # biological_process 20170111: Gammaproteobacteria_PTN001015057 participates in tRNA wobble uridine modification (GO:0002098) 20170111: Archaea_PTN002302630 does NOT participate in mitochondrial respiratory chain complex I assembly (GO:0032981) 20170111: Eukaryota_PTN000354502 participates in mitochondrial respiratory chain complex I assembly (GO:0032981) 20170111: Eumetazoa_PTN001014783 participates in sarcosine catabolic process (GO:1901053) 20170111: Proteobacteria_PTN000354644 participates in D-alanine catabolic process (GO:0055130) 20170111: Dikarya_PTN001014663 participates in retrograde transport, endosome to Golgi (GO:0042147) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).