# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
15 Mar 2016: Updated by: TOUCHUP-v1.14
25 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20150709: Eukaryota_PTN000352619 contributes to function RNA binding (GO:0003723) 

# cellular_component
20150709: Eukaryota_PTN000352619 is found in cytoplasmic mRNA processing body (GO:0000932) 
20150709: Eukaryota_PTN000352619 is found in U4/U6 x U5 tri-snRNP complex (GO:0046540) 
20150709: Eukaryota_PTN000352619 is found in Lsm1-7-Pat1 complex (GO:1990726) 
20150709: Eukaryota_PTN000352619 is found in catalytic step 2 spliceosome (GO:0071013) 
20150709: Eukaryota_PTN000352619 is found in U6 snRNP (GO:0005688) 
20150709: Eukaryota_PTN000352619 is found in precatalytic spliceosome (GO:0071011) 

# biological_process
20150709: Eukaryota_PTN000352619 participates in mRNA splicing, via spliceosome (GO:0000398) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
This family contains the highly conserved Lsm2 protein. It is found in two seven membered Lsm rings, each containing Lsm2-7, and containing either Lsm1 or Lsm8. The complex containing Lsm8 localizes to the nucleus where it binds the U6 snRNA and is involved in spliceosomal splicing. The complex containing Lsm1 is cytoplasmic where it associates with the Pat1p decapping enzyme and Xrn1p exoribonucleases and is involved in mRNA degradation.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).