# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20140814: Eukaryota_PTN000349139 has function ubiquitin-protein transferase activity (GO:0004842) 

# cellular_component
20140814: Eukaryota_PTN000349139 is found in BRCA1-A complex (GO:0070531) 
20140814: Eukaryota_PTN000349139 is found in BRCA1-BARD1 complex (GO:0031436) 
20140814: Eukaryota_PTN000349139 is found in plasma membrane (GO:0005886) 

# biological_process
20140814: Eukaryota_PTN000349139 participates in negative regulation of histone acetylation (GO:0035067) 
20140814: Eukaryota_PTN000349139 participates in positive regulation of cell cycle arrest (GO:0071158) 
20140814: Eukaryota_PTN000349139 participates in regulation of cell proliferation (GO:0042127) 
20140814: Eukaryota_PTN000349139 participates in double-strand break repair via homologous recombination (GO:0000724) 
20140814: Eukaryota_PTN000349139 participates in negative regulation of fatty acid biosynthetic process (GO:0045717) 
20140814: Eukaryota_PTN000349139 participates in positive regulation of histone acetylation (GO:0035066) 
20140814: Eukaryota_PTN000349139 participates in positive regulation of transcription from RNA polymerase II promoter (GO:0045944) 
20140814: Chordata_PTN000349142 participates in dosage compensation by inactivation of X chromosome (GO:0009048) 
20140814: Chordata_PTN000349142 participates in chordate embryonic development (GO:0043009) 
20140814: Sauria_PTN001417484 does NOT participate in dosage compensation by inactivation of X chromosome (GO:0009048) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).