# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150522: root_PTN000343556 has function structural constituent of ribosome (GO:0003735) # cellular_component 20150522: cellular organisms_PTN000343558 is found in cytosolic large ribosomal subunit (GO:0022625) 20150522: Eukaryota_PTN000343651 is found in mitochondrial large ribosomal subunit (GO:0005762) 20150522: Bacteria _PTN000343716 is found in cytosolic large ribosomal subunit (GO:0022625) # biological_process 20150522: root_PTN000343556 participates in cytoplasmic translation (GO:0002181) 20150522: Eukaryota_PTN000343651 participates in mitochondrial translation (GO:0032543) 20150522: Eukaryota_PTN000343651 does NOT participate in cytoplasmic translation (GO:0002181) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).