# HISTORY 04 Aug 2016: Updated by: TOUCHUP-v1.21 # molecular_function 20160428: Eukaryota_PTN000336234 has function lipid binding (GO:0008289) # cellular_component 20160428: Eukaryota_PTN000336234 is found in endoplasmic reticulum (GO:0005783) 20160428: Fungi_PTN001412650 is found in ERMES complex (GO:0032865) # biological_process 20160428: Fungi_PTN001412650 participates in mitochondrion-ER tethering (GO:1990456) 20160428: Fungi_PTN001412650 participates in phospholipid transport (GO:0015914) 20160428: Fungi_PTN001412650 participates in protein import into mitochondrial outer membrane (GO:0045040) 20160428: Fungi_PTN001412650 participates in mitochondrial outer membrane translocase complex assembly (GO:0070096) 20160428: Fungi_PTN001412650 participates in mitochondrial genome maintenance (GO:0000002) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).