# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20151117: Eukaryota_PTN001412288 has function nucleocytoplasmic transporter activity (GO:0005487) 20151117: Eukaryota_PTN001412288 has function nuclear localization sequence binding (GO:0008139) # cellular_component 20151117: Eukaryota_PTN001412288 is found in nuclear pore (GO:0005643) # biological_process 20151117: Eukaryota_PTN001412288 participates in protein import into nucleus (GO:0006606) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES This family contains the channnel nucleoporin subunit NUP58 (aka Sp NUP45). Note that Sc NUP49 is missing from this tree. In Panther 10, Sc NUP49 is misplaced in PTHR23198, the family for Sc NUP100, NUP116, & NUP145N, [Hoelz et al. 2011 (PMID:21495847), Aitchison and Rout 2012 (PMID:22419078), and Kabachinski and Schwartz 2015 (PMID:26046137)]. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).