# HISTORY 07 Sep 2016: Saved by pascalegaudet using Paint 2.22 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 07 May 2016: Updated by: TOUCHUP-v1.18 # molecular_function 20140613: Eukaryota_PTN000996416 has function protein kinase binding (GO:0019901) 20160907: Eukaryota_PTN000996416 has function protein complex scaffold (GO:0032947) # cellular_component 20140613: Eukaryota_PTN000996416 is found in pre-autophagosomal structure membrane (GO:0034045) 20140613: Eukaryota_PTN000996416 is found in ATG1/ULK1 kinase complex (GO:1990316) # biological_process 20140613: Eukaryota_PTN000996416 participates in positive regulation of protein phosphorylation (GO:0001934) 20140613: Eukaryota_PTN000996416 participates in autophagosome assembly (GO:0000045) 20160907: Eukaryota_PTN000996416 participates in cellular response to nitrogen starvation (GO:0006995) 20160907: Eukaryota_PTN000996416 participates in mitophagy (GO:0000422) 20160907: Eukaryota_PTN000996416 participates in pexophagy (GO:0030242) 20160907: Eukaryota_PTN000996416 participates in glycophagy (GO:0061723) 20160907: Eukaryota_PTN000996416 participates in reticulophagy (GO:0061709) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES ATG17 family, but ATG17 from Yeast is missing in the tree ! Rgulates ATG1 autophosphorylation with ATG13 in yeast (absent in treee) plays particularly a role in pexophagy and nucleophagy. With ATG13, is required for ATG1 activation by autophosphorylation of 'Thr-226'. Recruits ATG9 to the pre-autophagosomal structure. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).