# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function

# cellular_component
20150915: Eukaryota_PTN000320122 is found in U5 snRNP (GO:0005682) 

# biological_process

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
This family contains a subunit of the U5 snRNP (called LIN1, aka SNU40 in S. cerevisiae, or SD2BP2 in vertebrates) involved in splicing via the spliceosome.
There is some discrepancy in the existing annotations/literature regarding whether this protein is also part of the U4/U6.U5 tri-snRNP, but the weight seems slightly more in favor of not part of the tri-snRNP, so I have not propagated this annotation that is present for Sc LIN1.
- Hacker et al. 2008 (PMID:18953335) - Shows LIN1 in Figure 1 part A listing it as a component of affinity-purified tri-snRNPs from S. cerevisiae.
- Stevens et al. 2001 (PMID:11720284) - indicated that S. cerevisiae LIN1 (aka SNU40) is NOT present in the U4/U6•U5 snRNP.
- Laggerbauer et al. 2005 (PMID:15840814) - indicated that Human CD2BP2 is NOT part of the tri-U4/U6•U5 snRNP.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).